克莱门特的首次个展于1971年在罗马举行。他的作品探索了身份的概念。他与意大利概念艺术家Alighiero Boetti一起学习，并与住在意大利的美国艺术家Cy Twombly会面。 Boetti和Clemente于1973年前往印度。在那里，克莱门特遇到了印度佛教的解放者或缺乏自我的概念，这成为他作品中的一个主要主题元素。他在印度马德拉斯开设了一家工作室，并与印度奥里萨邦和斋浦尔的画家合作，创作了1981年的系列水粉画，名为Francesco Clemente Pinxit。 1982年，克莱门特搬到了纽约市，在那里他迅速成为了艺术界的一员。从那时起，他主要居住在三个不同的城市：那不勒斯，意大利;印度瓦拉纳西;和纽约市。 Francesco Clemente成为意大利艺术家之间所谓的Transavanguardi或Transavantgarde运动的一部分。在美国，该运动被认为是更广泛的新表现主义运动的一部分。这是对概念和极简主义艺术的敏锐反应。新表现主义者回归比喻艺术，象征主义，并在作品中探索情感。新表现主义在20世纪70年代后期出现，并在20世纪80年代前半期开始主导艺术市场。由于女性艺术家的疏忽或边缘化，支持全男性表演，该运动受到了尖锐的批评。
Clement’s first solo exhibition was held in Rome in 1971. His work explores the concept of identity. He studied with Italian conceptual artist Alighiero Boetti and met with American artist Cy Twombly, who lives in Italy. Boetti and Clemente traveled to India in 1973. There, Clement met the liberation of Indian Buddhism or the concept of lack of self, which became a major theme in his work. He opened a studio in Madras, India, and worked with painters from Orissa and Jaipur in India to create the 1981 series of gouaches called Francesco Clemente Pinxit. In 1982, Clement moved to New York City, where he quickly became a member of the art world. Since then, he has lived mainly in three different cities: Naples, Italy; Varanasi, India; and New York City. Francesco Clemente became part of the so-called Transavanguardi or Transavantgarde movement between Italian artists. In the United States, the movement is considered part of a broader new expressionist movement. This is a keen reaction to concepts and minimalist art. The new expressionist returns to metaphorical art, symbolism, and explores emotions in his works. New expressionism emerged in the late 1970s and began to dominate the art market in the first half of the 1980s. The campaign was sharply criticized for its support for all-male performances due to the negligence or marginalization of female artists.